Pritasa, Muthia Ulfa (2018) Pengaruh Pemberian Ekstrak Biji Melinjo (Gnetum Gnemon) Terhadap Kadar Trigliserida Pada Tikus dengan Diet Tinggi Lemak. Diploma thesis, Universitas Andalas.
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Abstract
Melinjo (Gnetum gnemon) seed extract contains many kinds of stilbenoid as known as “Melinjo Resveratrol”. Resveratrol decreases triglyceride by oxidating LDL-Cholesterol and modulating lipid metobolism. The purpose of this study is to identify the effect of melinjo seed extract in triglceride level of high fat diet rats. This is an experimental study with randomized pre-post test control group design consisted of 5 groups (K-, K+, P1, P2, and P3). Group P1 was given 250 mg/kg/day, group P2 500 mg/kg/day, and group P3 2000 mg/kg/day of melinjo seed extract started from the 16th day to the end of the study. Triglyceride was measured by GPO-PAP method. The data were analyzed by paired T-test. Triglyceride level in group K- group decreased from 89,96 mg/dl to 80,66 mg/dl, group K+ decreased from 90,36 mg/dl to 84,64 mg/dl, group P1 decreased from 92,9 mg/dl to 76,3 mg/dl, group P2 decreased from 90,68 mg/dl to 85,22 mg/dl, and group P3 increased from 73,5 mg/dl to 83,4 mg/dl. Based on paired T-test analysis showed a non-significant decrease in triglyceride. The conclusion of this study showed that melinjo seed extract is unable to reduce triglyceride level of high fat diet rats. Key words: High fat diet, melinjo seed extract, triglyceride
| Item Type: | Thesis (Diploma) |
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| Primary Supervisor: | Dra. Yustini Alioes, M.Si, Apt |
| Subjects: | R Medicine > RM Therapeutics. Pharmacology |
| Divisions: | Fakultas Kedokteran |
| Depositing User: | S1 Pendidikan Kedokteran |
| Date Deposited: | 09 May 2018 15:15 |
| Last Modified: | 09 May 2018 15:15 |
| URI: | http://scholar.unand.ac.id/id/eprint/33561 |
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