HUBUNGAN RASIO NEUTROFIL LIMFOSIT (RNL) DENGAN STADIUM KLINIS PASIEN KARSINOMA KOLOREKTAL DI RSUP DR. M. DJAMIL PADANG TAHUN 2022-2023

Rahmadini, Aulia (2024) HUBUNGAN RASIO NEUTROFIL LIMFOSIT (RNL) DENGAN STADIUM KLINIS PASIEN KARSINOMA KOLOREKTAL DI RSUP DR. M. DJAMIL PADANG TAHUN 2022-2023. Diploma thesis, Universitas Andalas.

[img] Text (Cover dan Abstrak)
Cover-Abstrak.pdf - Published Version
Download (183kB)
[img] Text (BAB 1 Pendahuluan)
Bab 1 Pendahuluan.pdf - Published Version
Download (166kB)
[img] Text (BAB 7 Penutup)
Bab 5 Penutup.pdf - Published Version
Download (150kB)
[img] Text (Daftar Pustaka)
Daftar Pustaka (2).pdf - Published Version
Download (185kB)
[img] Text
Skripsi Full Text.pdf - Published Version
Restricted to Repository staff only
Download (3MB)

Abstract

Colorectal carcinoma is a malignant disease characterized by abnormal cell proliferation in the colon and rectum. It ranks third globally in cancer incidence, with 1.931.590 cases reported in 2020. Various factors influence its clinical stage, including inflammatory cell proportions in the perivascular area, which can expedite tumor growth, invasion, and metastasis. The neutrophil lymphocyte ratio (NLR) serves as a predictive marker for the clinical stage of patients. An observational analytical study conducted at RSUP Dr. M. Djamil Padang analyzed 141 colorectal carcinoma patients from 2022-2023. The results show majority of patients were male (51%) aged over 50 years (65.95%), with the stage III being the most prevalent (42.55%). Notably, a substantial proportion of patients exhibited high neutrophil counts (>7.5x103/mm3) (60.28%), while lymphocyte counts mostly results within the normal range (1-3.5x10^3/mm3) (61.70%). Receiver Operating Characteristic (ROC) curve analysis to determine the Area Under Curve (AUC) provides a cut off point value of 4.79 with a sensitivity value of 83% and a specificity of 82%. Bivariate analysis with the chi square test between RNL and clinical stages shows p=0.022. Based on this research, there is a relationship between the neutrophil lymphocyte ratio and the clinical stage of colorectal carcinoma patients at RSUP Dr. M. Djamil Padang in 2022-2023. Keywords: Clinical stage, colorectal carcinoma, neutrophil-to-lymphocyte rasio

Item Type: Thesis (Diploma)
Primary Supervisor: Dr. dr. Noza Hilbertina, M.Biomed, SpPA, Subsp D.H.B(K)
Uncontrolled Keywords: Karsinoma kolorektal, rasio neutrofil limfosit, stadium klinis
Subjects: R Medicine > R Medicine (General)
Divisions: Fakultas Kedokteran
Depositing User: S1 Pendidikan Kedokteran
Date Deposited: 27 May 2024 07:47
Last Modified: 27 May 2024 07:47
URI: http://scholar.unand.ac.id/id/eprint/467586

Actions (login required)

View Item View Item
eSkripsi Universitas Andalas is powered by EPrints 3 which is developed by the School of Electronics and Computer Science at the University of Southampton. More information and software credits.