PERBANDINGAN EFEKTIFITAS ANALGETIK TRAMADOL INTRAVENA DAN PARACETAMOL INTRAVENA DALAM MENGATASI NYERI AKUT PASCA PERCUTANEOUS NEPHROLITHOTOMY (PCNL) DI RSUP DR. M. DJAMIL PADANG

Saleh, Leonard Khriestsandi (2023) PERBANDINGAN EFEKTIFITAS ANALGETIK TRAMADOL INTRAVENA DAN PARACETAMOL INTRAVENA DALAM MENGATASI NYERI AKUT PASCA PERCUTANEOUS NEPHROLITHOTOMY (PCNL) DI RSUP DR. M. DJAMIL PADANG. Masters thesis, Universitas Andalas.

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Abstract

Introduction: Tramadol is a synthetic aminosyclohexanol that acts centrally with weak opioid agonist. Paracetamol is analgesia and anti-pyretic properties for both adults and children with very low incidence of side effects. Percutaneous nephrolilthotomy (PCNL) as first-line therapy in cases of kidney stones measuring more than 20 mm. Paracetamol analgesia is preferred over opiods because of the minimal side effects. Objective: To compare the effectiveness of acute pain reduction after PCNL procedure in patients treated with intravenous tramadol and intravenous paracetamol analgesics at Dr. M. Djamil Hospital Padang. Methods: This study used an analytic method with a single-blind randomized controlled trial design. The research was conducted at Dr. M. Djamil Hospital in November-December 2022. Sampling was done by modified slovin. Result: The effectiveness of paracetamol for postoperative pain assessed from the Visual Analog Scale showed that the group of patients given intravenous Paracetamol after PCNL surgery obtained a lower VAS value compared to the use of intravenous tramadol, but the difference did not show a significant number in statistical tests. Conclusion: There is no significant difference between the use of both paracetamol and tramadol analgesics in the management of acute pain after PNCL. Keywords: Tramadol, Paracetamol, PCNL, kidney stones

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