PERBEDAAN KADAR SUPEROKSIDE DISMUTASE (SOD) PADA REMAJA DENGAN DISMENORE PRIMER DAN TANPA DISMENORE

YANTI, YANTI (2015) PERBEDAAN KADAR SUPEROKSIDE DISMUTASE (SOD) PADA REMAJA DENGAN DISMENORE PRIMER DAN TANPA DISMENORE. Masters thesis, UNIVERSITAS ANDALAS.

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Abstract

pathology, cramps last for one day or more and accaompanied by nausea, diarrhea and headache. Problems cause by dysmenorrhea are an increase in school attendance inadolescents resulting in low academic grades of students. Superokside Dismeutase (SOD) is a bioactive ingredient that is know to be an antioxidants, protecting cells against harmful SOD oxidants (free radicals) sod convert superoxide anion into hydrogen perokxide and oxygen, often reffered to as aprimary defense agains oxidative stress. In primary dymenorea increased uterine activity/ increased uterine contractions cause arteriolar vasospasm resulting in ischemia and lower abdominal cramping and increased alots of oxygen produced. Free radicals and taking antioxidants superoxside dismutase which will relate to the primary dysmenorrheal. This study aims to determine the differences in the levels of superoxide dismutase in adolencents with and without dysmenorrheal. This study is a comparative observasional cross-sectional design, the study conducted at Biomedical Laboratory Medical Faculty of Andalas University in May-Juli 2014. The sample consisted of two groups of 34 samples each. The level of SOD using Elisa method. Data were analyzed by using Test Mann-whitney with p<0,05 considered statistically significant. The result obtained by the average levels of SOD adolescents who experienced dysmenorrea is 36,76u/ml, with a value of p>0,05 (0,345). The conclusion of the study is no significant difference SOD levels in adolescents with and without dysmenorrea. Keywords : Adolescent, Dysmenorrea, Superoxide Dismutase, Antioxcidant

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