KEEFEKTIFAN MISOPROSTOL PERORAL SEBAGAI PEMATANGAN SERVIKS PADA KETUBAN PECAH DINI KEHAMILAN ATERM DENGAN SKOR BISHOP ≤ 4 DI PADANG

Ranni, Fistri Khaisari (2014) KEEFEKTIFAN MISOPROSTOL PERORAL SEBAGAI PEMATANGAN SERVIKS PADA KETUBAN PECAH DINI KEHAMILAN ATERM DENGAN SKOR BISHOP ≤ 4 DI PADANG. Masters thesis, Universitas Andalas.

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Abstract

Background: Misoprostol is a synthetic prostaglandin E1 analogue, is used in cervical ripening in pregnancy by increasing the activity of collagenase and change the composition of proteoglycans, causes the softening and thinning of the cervix thereby increasing the success rate of drip induction and spontaneous labor. Objectives: To compare the effectivity of cervical ripening at 25 ug oral misoprostol with those not given to premature rupture of membranes at term with a Bishop score less than or equal to (≤) 4. Place: Obstetrics and Gynecology Department Dr. M. Djamil Hospital Padang and Reksodiwiryo Hospital Padang . Design: randomized controlled clinical trials without blinding. Materials and methods: From November 2013 until August 2014 had collected 14 samples of research which is the premature rupture of membranes at term patients who met the inclusion criteria, a total of 7 people given misoprostol and 7 are not given misoprostol. All samples were examined bishop score, ctg and blood samples. Results: There is a significant difference in the increase of Bishop score at 25 ug oral misoprostol with those not given to premature rupture of membranes at term with a Bishop score less than or equal to (≤) 4 (p = 0.000) and the side effects are not obtained. Conclusion: There is a effectivity of cervical ripening at 25 ug oral misoprostol to premature rupture of membranes at term with Bishop scores less than or equal to (≤) 4. Key words: Cervical ripening, premature rupture of membranes at term,

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