ENCAPSULATION OF MAGNETIC-LUMINESCENT Fe3O4/CARBON QUANTUM DOT NANOCOMPOSITES USING ZIF-8 METAL-ORGANIC FRAMEWORK (MOF)

Yandora, Chika (2026) ENCAPSULATION OF MAGNETIC-LUMINESCENT Fe3O4/CARBON QUANTUM DOT NANOCOMPOSITES USING ZIF-8 METAL-ORGANIC FRAMEWORK (MOF). S1 thesis, Universitas Andalas.

	Text (01. Cover dan Abstrak) 01. Cover dan Abstrak.pdf - Published Version Download (193kB)
	Text (02. BAB I) 02. BAB I.pdf - Published Version Download (268kB)
	Text (03. BAB V) 03. BAB V.pdf - Published Version Download (139kB)
	Text (04. Daftar Pustaka) 04.Daftar Pustaka.pdf - Published Version Download (283kB)
	Text (05. Skripsi full text) 05. Skripsi full text.pdf - Published Version Restricted to Repository staff only Download (3MB) | Request a copy

Abstract

Fe3O4/CQD magnetic-luminescent nanocomposites have potential as bioimaging materials because they combine magnetic and fluorescent properties in a single system. However, the combination of Fe3O4 and CQDs has limitations, namely the occurrence of a quenching effect that causes a decrease in fluorescence intensity, as well as limited dispersion stability in both aqueous and biological media. Therefore, surface modification of the Fe3O4/CQD nanocomposite is required through encapsulation using a biodegradable material, namely Zeolitic Imidazolate Framework-8 (ZIF-8). This study aims to synthesize Fe3O4/CQD@ZIF-8 nanocomposites via the in situ self-assembly method and to investigate the effect of variations in the Zn2+:2-Hmim precursor on fluorescence intensity and dispersion stability. The successful synthesis of the Fe3O4/CQD@ZIF-8 nanocomposite was characterized using X-ray diffraction (XRD), Fourier transform infrared spectroscopy (FTIR), and atomic force microscopy (AFM). Dispersion stability was analyzed by measuring the zeta potential, while fluorescence intensity was analyzed using a fluorescence spectrophotometer. The results of XRD, FTIR, and AFM characterization showed that ZIF-8 successfully encapsulated the Fe3O4/CQD nanocomposites. Encapsulation using ZIF-8 increased the fluorescence intensity, with the highest intensity obtained at a precursor ratio of 0.75 g Zn2+:1.65 g 2-Hmim. Meanwhile, the sample with a precursor ratio of 0.1 g Zn2+:0.22 g 2-Hmim exhibited the best dispersion stability with a zeta potential of -39.2 mV. The results indicate that the encapsulation of Fe3O4/CQD nanocomposites using ZIF-8 was successfully achieved across all investigated precursor ratios. Increasing the Zn2+-to-2-Hmim precursor ratio increased the fluorescence intensity but decreased the dispersion stability. Therefore, optimization of the precursor ratio is necessary to obtain Fe3O4/CQD nanocomposites with high fluorescence intensity and good dispersion stability. Keywords: bioimaging, dispersion stability, Fe3O4/CQD, fluorescence intensity, luminescent magnetic nanocomposites, ZIF-8

Actions (login required)

View Item