PENGARUH PENAMBAHAN EKSTRAK DAUN KERSEN (Muntingia Calabura L.) PADA NANOFIBER PLA (Polylactic Acid) HASIL ELECTROSPINNING SEBAGAI ANTIBAKTERI

Melanni, Efendi (2024) PENGARUH PENAMBAHAN EKSTRAK DAUN KERSEN (Muntingia Calabura L.) PADA NANOFIBER PLA (Polylactic Acid) HASIL ELECTROSPINNING SEBAGAI ANTIBAKTERI. Diploma thesis, Universitas Andalas.

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Abstract

Nanofiber is a fiber with a diameter of less than 100 to 500 nanometers. Nanofiber is one example of nanotechnology that can be made by electrospinning. Electrospinning is considered more efficient than other fiber manufacturing methods due to its versatile, easy-to-perform, and cost-effective nature. This makes it suitable for biomedical applications. Various types of polymers, both natural and synthetic, can be used to make different types of nanofibers. This study examines the effect of adding kersen leaf extract or commonly called seri leaves to PLA (Polylactic Acid) from electrospinning nanofibers. The fibers made can be used in various fields, including antibacterial testing. Due to its active ingredients, flavonoids, alkaloids, and terpenoids, kersen leaves can be said to have antibacterial properties. Using the electrospinning method, a solution made from a mixture of PLA (Polylactic Acid) and kersen leaf extract was tested aiming to produce nanofibers that have antibacterial properties in them. By combining 30%, 50%, and 70% concentrations of Muntingia extract with a constant concentration of PLA (Polylactic Acid), three types of fibers were made. The resulting fibers were examined using scanning electron microscopy (SEM), then their average diameter was calculated with imageJ, and evaluated to determine their antibacterial properties. The three fiber concentrations were tested for their ability against Staphylococcus aureus and Escherichia coli bacteria. The nanofiber consisting of 30% kersen leaf extract and 70% PLA (Polylactic Acid) polymer had an average diameter of 1.199 μm. In antibacterial testing, a zone of inhibition of 17.68 mm was found and showed that the fiber consisting of 70% kersen leaf extract and 30% PLA polymer had strong antibacterial power against S. Aureus bacteria. This study shows the addition of kersen leaf extract to electrospinning PLA (Polylactic Acid) fiber has potential as an antibacterial because of its zone of inhibition against bacteria.

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