EVALUASI PENGGUNAAN OBAT ANTIHIPERLIPIDEMIA PADA PASIEN STROKE ISKEMIK DI RSSN BUKITTINGGI TAHUN 2017

Zahratul, Miska (2018) EVALUASI PENGGUNAAN OBAT ANTIHIPERLIPIDEMIA PADA PASIEN STROKE ISKEMIK DI RSSN BUKITTINGGI TAHUN 2017. Diploma thesis, Universitas Andalas.

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Abstract

Evaluasi penggunaan obat perlu dilakukan untuk menjamin penggunaan obat yang aman, tepat dan efektif. Tujuan penelitian ini adalah untuk mengetahui karakteristik demografi, pola penggunaan obat dan kerasionalan penggunaan obat antihiperlipidemia pada pasien stroke iskemik di RSSN Bukittinggi tahun 2017. Metode penelitian yang digunakan adalah deskriptif dengan pengambilan data secara retrospektif. Dari 357 pasien yang memenuhi kriteria inklusi terdapat 60,20% pasien laki-laki dan 39,80% pasien perempuan. Stroke iskemik lebih banyak terjadi pada usia 55-64 tahun (38,10%). Hasil penelitian menunjukan bahwa obat yang paling banyak digunakan simvastatin (98,60%) pada terapi tunggal. Rasionalitas penggunaan antihiperlipidemia 100% tepat indikasi, tepat obat, tepat pasien, tepat dosis dan tepat frekuensi. Terdapat 38,90% obat berpotensi berinteraksi secara farmakokinetik. Berdasarkan tingkat keparahan potensi interaksi obat terdapat 0,30% obat berinteraksi secara moderat dan 38,60% mayor. Kata kunci: Evaluasi penggunaan obat, stroke iskemik, rasionalitas, interaksi Drug use evaluation needs to ensure the use of the drug is safe, appropriate and effective. The aims of this research are to determine the demographic characteristics, drug use patterns and rationality the use of antihyperlipidemic in ischemic stroke in RSSN Bukittinggi in 2017. The study used the descriptive method and data was taken retrospectively. Out of 357 patients who where included in inclusion criteria, 60.20% was female and 39.80% was male. Ischemic stroke was more common among the age group of 55 to 64. The result of the study showed that the most widely used drug was simvastatin (98.60%) in single therapy. The rationality of antihyperlipidemic used was 100% appropriate indications, appropriate drugs, appropriate patients, appropriate doses and appropriate frequency. There was 38.90% of drugs that potentially interacted with pharmacokinetically. Based on the severity of potential drug interactions, there was 0.30% of moderate interaction and 38.60% of major interaction. Keywords: Drug use evaluation, ischemic stroke, rationality, interaction

Item Type: Thesis (Diploma)
Primary Supervisor: Yori Yuliandra, M.Farm, Apt
Subjects: R Medicine > RS Pharmacy and materia medica
Divisions: Fakultas Farmasi
Depositing User: s1 Fakultas Farmasi
Date Deposited: 23 Oct 2018 08:35
Last Modified: 23 Oct 2018 08:35
URI: http://scholar.unand.ac.id/id/eprint/40082

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