PERBEDAAN RERATA KADAR P-SELEKTIN SERUM DAN TROMBOSIT PADA PREEKLAMSIA BERAT DAN EKLAMSIA

Yudha, Meiriza Kartika (2016) PERBEDAAN RERATA KADAR P-SELEKTIN SERUM DAN TROMBOSIT PADA PREEKLAMSIA BERAT DAN EKLAMSIA. Masters thesis, Universitas Andalas.

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Abstract

Objective: To know the differences between the mean serum levels of p-selectin and platelet of severe preeclampsia and eclampsia. Method: This research was conducted by cross sectional method in maternity emergency room of obstetrics and gynecology department of Central General Hospital of Dr. M. Djamil Padang from June 2015 through the sample size is met with 20 patients of severe preeclampsia and 8 patients of eclampsia, who met the inclusion criteria and there is no exclusion criteria. Then performed statistical analysis using t-test to determine differences in mean serum levels of p-selectin and platelet of severe preeclampsia and eclampsia. Result: The mean serum levels of p-selectin in severe preeclampsia is 120.7 ± 26.9 ng / ml and in eclampsia is 241.5 ± 19.1 ng / ml. Differences in mean serum levels of pselectin in the two groups was statistically significant (p = 0.000). The mean platelet levels in severe preeclampsia is 263 690 ± 31371.9 / mm3 and in eclampsia is ± 177 875 83011.9 / mm3. Differences in mean platelet levels in the two groups was statistically significant (p = 0.000). Conclusion: Activated platelets at eclampsia is higher than severe preeclampsia, which is indicated by the high levels of p-selectin serum and low platelets remaining in eclampsia than severe preeclampsia. Keywords: P-selectin, Platelet, Severe Preeclampsia, Eclampsia.

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