STANDARDISASI SIMPLISIA DAN EKSTRAK DAUN GANDARUSA (Justicia gendarussa Burm. F.)

Rafiqha, Nurul Fadjri (2017) STANDARDISASI SIMPLISIA DAN EKSTRAK DAUN GANDARUSA (Justicia gendarussa Burm. F.). Diploma thesis, Universitas Andalas.

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Abstract

In Papua, gandarusa (Justicia gendarussa Burm. F.) is traditionallyused as men antifertility. Quality of gandarusa herbal material and extract are not available in Indonesian Herbal Pharmacopeae (FHI) yet. Therefore, there is a need to establish quality from them.Gandarusa leaves were collected from Tawangmangu, Solo, and Padang region. Specific parameters for herbal material suggested: macroscopic parameters leaves lancet-shaped, leaves tip pointed, green brown, edge of the leave slippery, leave surface smooth, characteristic odor, bitter taste; microscopic observation at magnification 400x found thrichomes form rod shape, anular vessels, upper epidermis, epidermis with stomata anomocytic type, epidermis with glandular scales, sclerenchyma; water soluble extract should be not less than 12.10%; ethanol soluble extract should be not less than 3.12%. Non specific parameters for herbal material suggested: loss on drying should be not more than 10%; ash content should be not more than 14.66%; acid insoluble ash content should be not more than 2.57%; Specific parameters for ethanol extract suggested: blackish viscous extract brown colored, bitter taste, characteristic odor. Non specific parameters for ethanol extract suggested: yield should be not less than 8.85%; ash content should be not more than 38.64%; acid insoluble ash content should be not more than 2.57%; the water content should be not more than 15.86%. Determination of total flavonoid content was calculated as rutin. It’s content for herbal material should benot less than 0.057% and for the extract should be not less than 0.38%. Thin layer chromatography (TLC) pattern should six spot for herbal material and seven spot for extract with the solventethyl acetate-methanol-water (15:3:2). Detection of spot with sitroborat reagent found. Rf 0.40 and 0.38 for herbal material and extract respectively, which were are similar to Rf of rutin.

Item Type: Thesis (Diploma)
Subjects: R Medicine > RS Pharmacy and materia medica
Divisions: Fakultas Farmasi
Depositing User: s1 Fakultas Farmasi
Date Deposited: 02 Feb 2017 06:50
Last Modified: 27 Mar 2017 08:37
URI: http://scholar.unand.ac.id/id/eprint/21503

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