THE POTENTIAL OF LIMA BEAN FLOUR (Phaseolus lunatus) IN IMPROVING COGNITIVE FUNCTION AND GROWTH RECOVERY OF MALNUTRITION RATS

Azizah, Amatu Zikrah (2023) THE POTENTIAL OF LIMA BEAN FLOUR (Phaseolus lunatus) IN IMPROVING COGNITIVE FUNCTION AND GROWTH RECOVERY OF MALNUTRITION RATS. Diploma thesis, Universitas Andalas.

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Abstract

Malnutrition is a condition characterized by inadequate or excessive consumption of nutrients, resulting decrease cognitive abilities, metabolic disorders, learning disabilities, growth retardation, decreased immune system, and the risk of death. The percentage of malnutrition prevalence in Indonesia was still relatively high, around 21,6%. This research aims to investigate the potential of lima beans (Phaseolus lunatus) in promoting growth recovery and improving cognitive function in malnourished rats. Four groups of male white rats were included in this study: The control group (P1), Malnutrition group (P2), Malnutrition + 25% Lima Bean group (P3), and Malnutrition + 50% Lima Bean group (P4). Morphometric analysis was used to assess growth recovery. Cognitive tests included Y-Maze, Novel Object Recognition Test (NORT), and Water Maze by Morris (MWM) test, and histopathological examination of the brain sections was conducted on the cerebral cortex and hippocampus by hematoxylin and eosin stains. This study found that lima bean flour increased body weight, body length, tail length, and ear length in malnourished rats at 50% lima bean concentration, similar to the control group. Lima bean flour showed neuroprotective on the cerebral cortex and hippocampus by lowering the percentage of degenerated cells and increasing cognitive and behavioral.

Item Type: Thesis (Diploma)
Primary Supervisor: Dr. Rita Maliza
Uncontrolled Keywords: Malnutrition, Phaseolus lunatus, growth recovery, cognitive function, neuroprotective.
Subjects: Q Science > Q Science (General)
Q Science > QM Human anatomy
Q Science > QP Physiology
Divisions: Fakultas Matematika dan Ilmu Pengetahuan Alam > Biologi
Depositing User: S1 Biologi Unand
Date Deposited: 19 Sep 2023 01:27
Last Modified: 19 Sep 2023 01:27
URI: http://scholar.unand.ac.id/id/eprint/214327

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