Hubungan Jenis Infeksi Bakteri Vagina Berdasarkan Pewarnaan Gram Dengan Kejadian Ketuban Pecah Dini Preterm

Bayu, Permana (2021) Hubungan Jenis Infeksi Bakteri Vagina Berdasarkan Pewarnaan Gram Dengan Kejadian Ketuban Pecah Dini Preterm. Masters thesis, Universitas Andalas.

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Abstract

Introduction: Premature rupture of membranes (PROM) is defined as the rupture of the membranes before delivery. If the rupture of the membranes occurs before 37 weeks of gestation. One of the most common risk factors is infection. Bacterial transmission comes from an ascending vaginal infection to the amnion. The rate of morbidity in infants born with infection in premature rupture of membranes is quite high. Currently there are many good methods to determine the cause of the bacteria present, but the cost and time of processing are still challenges that must be solved. Appropriate and prompt use of antibiotics is necessary. Rapid identification of bacteria by Gram stain can be applied to determine which initial antibiotic is more targeted. This is expected to help reduce the excessive use of antibiotics so that it has a role to reduce the incidence of antibiotic resistance. Objective: To determine the relationship between types of vaginal bacterial infections based on Gram staining with the incidence of preterm premature rupture of membranes. Methods: This research is an analytical observational study using a cross sectional study design. Data were taken using consecutive sampling in patients with preterm premature rupture of membranes at RSUP Dr. M. Djamil. Results: Vaginal bacteria with Gram stain were found in 90% of the PROM cases examined. The bacteria identified were dominated by 46.7% by Gram negative. PROM is not always followed by a bacterial infection. About 10% found no bacterial infection found in cases. Conclusion: Vaginal bacterial infection and the incidence of preterm premature rupture of membranes have a strong relationship. Bacterial identification based on Gram stain has a place to apply.

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